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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d108b5ab2b7545c321abc7c8806ca8fe589dfb161b7a6aabe72cad0fe9a80ca' 
  AND token = 'ckeu09u+38vMPcd1D3OezgBQiE6mAQsuWo5SmAoFavs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}