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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '681ca3b6bbfdd70cd478f1994387e72ca9d53cfc571e552ff2f85bf21f36c353' 
  AND token = 'qEVbZS/UZphu19Xv+XTfNWO8vzb8TXetdLAD290/L7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}