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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5455b1831f5a2a214bdfea1b5c94096dc8661653abf4cc27d87e3643f2105702' 
  AND token = 'i4foh1SzqA4R/D4fOtF3p/EUXD3B4Ll36rOh4fJTq4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}