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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65424bb805cec1c1b976ee4dedc56e1e5165c6f076ef776bb170da1da053c05f' 
  AND token = 'OETR4zD+3Iq/yKvn2N/ScOGtqMy1P/Gg231/s9ESJ4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}