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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea774085799f851d3920f558e814a1049ffdac6bd924b42aed738348e71c21e8' 
  AND token = '+2fTv4cOcNnKvzr6fSnVvNoDbYIpeDUQgwVOu5P+Hx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}