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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e55682e29dee3af278cc2dbe768d7b7984772afcdf428b75557e21bc800b829d' 
  AND token = 'RMsJezz98SSZr3wfcBt+GuRva+SHkgBnywz3Y5KuPxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}