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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '740a4b981b46c9ec4a5ce4a41e46928285c368c44f73a0032131840b7e6e77f4' 
  AND token = 'ou0uciJrNdiemnac/b+S/ctSgzCyGVtx19xZSi/Kyo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}