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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ed33abb5b9ff8c066edf380d7ee3dfe8130e7fdaabd07798ccd477731872c8d' 
  AND token = 'm0+K5gMDDOfneS7uQCfuxRbjIE/zx3c7WkUVghGn0Cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}