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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '182f818f291ecb0346f6ec97b60427e1c3d78b064404d833156f74a67cb4db99' 
  AND token = 'qAQPZmCsc8Cbw7gOTL4jUwBgv1LMPavdou2MnbXcB0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}