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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ac90be8da5deafadf46486110adc02f0627cd2d8210b8228cc7618b4455782f' 
  AND token = 'tpoECTUdwKyhPIwvJK2v1xQQZPUbSWNrNfA2DMinvHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}