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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e81ee9005aab949adfcec507a4088af30bfc924d28c3c07c14454aff101d11dc' 
  AND token = 'Czsbto0b0A2VOoJ3ghy9Bmx1MhNa/52UkKpBQ0FpMbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}