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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e16d7b3cb2ef2718e03c9af329808b2740b409e1c1f2500159c69de9768ea43c' 
  AND token = 'CNIdV3nrKxL6Dzqm5erZCigmF2FY6XOE+wiZdaEBwO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}