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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5e2b03016f125fe2c3ef12766c6ea6821377d5aabfafb5b8a490e3cd001f49c' 
  AND token = 'EqM0xz/2fkNPcwSoydqU6WhLn4QZr/vxYOpmp3KGWiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}