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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e2e55ea29c57b6971485c01d1e56fba7326fc913edb8d4f236e8ef72cb3e15b' 
  AND token = 'TpmFHxKA9/Qmn4osQPL9Pd0WaW1E5RhjabC34M013Rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}