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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2526c9766894a0eb6f82f6e5507060bb7fc5412aaa7fdb6040b885f99f13a4fc' 
  AND token = 'YyzcalLZNrwWN/D2ihCSdoxMg+iwOTRDufRl9Z99p78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}