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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77666585ba8d41fe39bb4989d3457f28bcf680bfd1c5f606718298d2e15c0b8f' 
  AND token = 'h5ESb/kvOKgm1GaNu2SRLULQ9YiRcBg70G8crHJp71Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}