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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2b33a6308c5811cce28d376c02c467d14e4fa857682732d3dabc18f2346b212' 
  AND token = 'htN+YTePieZsEEh0OikH/xUoUlpLrbKxx5L5PffnGBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}