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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bbb6b65da3fcb57c5a5af7262631c3abc28bc84fe20683e382c0b09c23f0c00' 
  AND token = '2tjPOmOsT1YtO8uIQ3DVFNIAMeMjhr0mQ5V1kPznFTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}