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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a155f641355520ea5b6700450f11e0c06e3a01b236ed07643b87b1eac1f3c8f' 
  AND token = 'p1GSkNF7ARJjxt8mqR0rPrpzCuMXXtL4GmSa8X3AB1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}