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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d83466ef80f83a6910a506e5604ec0c2b1d5765059807607530b67b53d99af8' 
  AND token = 'BGpVwJRGVADR6OGtgOZFuE+RSnRKfwrkcO1+7kJcPi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}