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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be213ac0ff5eb86474bfe10168b2c7c3ca178e8c61e287d1aea4ab066f1903db' 
  AND token = 'NpdCz4d8tx+Zs0WorngMhlfSWzFgdTx5bv8cVskSBh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}