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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '717c49dbcf277e34605be528edacb3fdc36db1362cf0089e47a11a444caa0b49' 
  AND token = '8ol5Ka4KHIZxIIRVSDVe/15v9cPI9xfqvwJeLvDU0UM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}