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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b3af8c0555a724a0f1d17a361e1470cb546c0497961c26d5bfa260a7fe8a266' 
  AND token = 'SsM0fJfU9Q4BREucCV3A13SXaFdy7eKPfKSOoLJvRgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}