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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a875b1bc52b8195226ef316833ffc4c51506e1e63075524569ade194e9c96e42' 
  AND token = '5U+YH1IqcOKartAfRoMBjr6qw0xi4UFpO/ZUm0TPuX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}