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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd59a6f21e64da6979887d4bc1a1dadc80995c22188fb7288c516706710675d4a' 
  AND token = '52vdUVXar0RYOU3ridr8WJ/Vjc/h0BAW2aensFdQ6Gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}