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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c865c012b7e266e33d8ab72d95c94929dd0e88058f7d76c6c4023befd957630f' 
  AND token = 'pxK3xLQGBTsrbNA6LLl6H7IoVgB+XVgalJysfOmTKn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}