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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7442e30aaf5187763b0e2f5e16c473df6c75ac65f7742c1e99faf25dc1081fa0' 
  AND token = 'C2Jofd/Et1nJMasPJ9AsNJbs4FaJ7KlQn+UKKBvBYRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}