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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e44ee0ce043d25fc3a1688f3245a0f9a32dc3f4419c312021a9acd979d434791' 
  AND token = 'MmiHfmELFo2+V0PlW6MSI1wsnt5Iba8L3pLW+61uMhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}