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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f0b720e17433b65020398016b8d5acdca54e50393ba9d53bcbf7793b29796be' 
  AND token = 'SgxGSMginqG0NsE534O8NdJIx/VcJR4jj+nPyAPIej0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}