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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1682eee1c50c4b021073a90c9d20da26c0be0d132fc5a33f8e7d253c53d1bbac' 
  AND token = '0vt0RTFsGjDJrIQ9rd/PMUyha62dbenRIhXTYBhvoJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}