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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64e228207a24b8e72753cbcd367aac422ad6ea20f8df50feff82282c12efcbce' 
  AND token = 'kPru4v1/0j/oEoxfyzVGnNyofMfQHFGD+XAr3XHxdww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}