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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e5702e0edb4ee3a3876975bb265dc88aa9335e74a74738204f3ef9e4cc2a740' 
  AND token = 'OkZWkzgB6l+wOozehX/sijp0FD9nemSO2aaIRgB8zGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}