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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '549a15e0af3cb0e34a9dc48d76ac15e03610afaf6ae3b29ed3100c13600a88cb' 
  AND token = 'drabwATVsOkaiXqBYzpOgLndKKlVOUO0dH09TEk0X8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}