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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a13ba33ef657e16e35724d94c203a47bb76507f0a6f14ae57200144b5fb94571' 
  AND token = 'fyo1Cuq5Xsq1hSMTMMZfigjly0bOMJ2HPSXPcXSUsfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}