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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e28eac25c66d968df76f02048e25e3b26dce25a7a43a62a14e411dc25098b483' 
  AND token = 'IbS6Upj0BIiBBf8Hd0qB92E0Nv7YDYD6KNeUA31YvA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}