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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3490961ffef6886d68def6138a62a006d687a0398afc9a2ebaebff15bedeb66' 
  AND token = 'jJMy9X+ou307frrejRF+gniQx8um8NTzyLDc4VBjuQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}