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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c1673f9b84a7c985a4fb2ba21fe3c94e8039ed22ffd76cd88e6c7941e00298f' 
  AND token = 'Amk1ulYu9oFgz0UYZXczUZbJz/SQ9BMQy/pLR3DBL80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}