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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '990bc44aa03eab3f21eb30319b20b9391bbf9c4f7bd89fa7935013cd4cfc9d50' 
  AND token = 'l+b7etw0n8F2SLGlThaQAEcSrLhoLJX6OwsX6KNtgzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}