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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c9cf093d4dd55ebefa9ff2a82c8fe99fda11c624af24d4dc70b3b832d3eb0cc' 
  AND token = 'Ryay9WB1n3SNMVMXWc+lUSOm99u6/sWU1xcKFTll0Ik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}