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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '737eeef3235a3cf68186f103cb8169795d8f90b0a035238e18bceaae880b9e7c' 
  AND token = '6cbAggDe+FYVUvjZzcGZonBRJI+5RcWAvV/OinByfPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}