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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfd12d9f91571554e86a8e205855f190b15914f45581d6f55f141ae0e694399c' 
  AND token = 'Du+OHsJS276sLm1Z5M2k6bgr0MLy/hVxgaENtnzzLb4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}