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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c49f5df77c2ad959bc8de2769c84351d081f287e51307f382abb30993112c055' 
  AND token = '9+oFe5pw/UtAygY6IhEoWBf3NMP3jOA4jl/10ewCfn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}