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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7aad162903720768115d94566d64ab3f1025024002d1736ef25ea7a441afe0e5' 
  AND token = 'JmWQ5/SFIPO6WMG+adGVa/BN7n6XIyvUSar6R0AX038=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}