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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cd59e8b73af2a3dfb6b5f6693703e00b311b80180f9e2cae4d8d128e1b5ca9a' 
  AND token = '5QzDXrPp+DZawvGrJ39KxLf2iLOxjb2pO0bS2bkLM9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}