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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dedc4245833658fbce95b573a6054fc5fce04ff942ed85f4dc90ad6fe5decf23' 
  AND token = 'FZuAimsaU8ZCc28Y7OhBJBORLHpHBDCcf9OmvHqlVVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}