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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cca06d51abf44461d1d58acb1f729a9ccbd8401292e757ccd2e03194e873cbe' 
  AND token = 'UChU+Th2T+PZzAzQSCOBP9bL55eq3F21btVOvsFU1Lw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}