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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9197d140a6ede1cfe0aad6c3c999b578a3ea66f3f1d4c7b74ffd6767858cd890' 
  AND token = 'uwkr+rHX2kQgUz5EEO4gckX8TJMXmJWAbU1hsQgAttQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}