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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12bd704e2d0d08f2cf4814afa8042c216430eefd0fda1b3658b77e51c2f55ef7' 
  AND token = 'dColmjubypmhU1eR0CK9oA57BlCIhtQc0TOwV7wAV58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}