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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84e892c900021469206e710c3917b01ca54b67b182b2896aa9ba2dcc19ddcc72' 
  AND token = 'taT0mPtMBDyM/fD21YDRn3dyakVUKsQ2Ds0vA4ugOCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}