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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '472c5b93e119510aeaf344b2d862175b14edeabbee952b6830916604759508e7' 
  AND token = 'PIU02Bi7lB729QMFTCE3aZh/wHR1yPTE3weEORz9hvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}